Clinical Validation

The Science Behind Our Products

Over the past decade, there has been a great deal of data generated by scientists and clinicians confirming the safety of Pre-Seed lubricant’s formula. This includes data published in peer-reviewed journals or as presentations at major medical meetings. Pre-Seed lubricant is covered by numerous issued U.S. and international patents.

Click on the selected study title below to view study summaries.


Effect of an Isotonic Lubricant on Sperm Collection and Sperm Quality. Fertility and Sterility. 2013; 99, 4 Ashok Agarwal, Ph.D., Helena Malvezzi, M.S., , Rakesh Sharma, Ph.D.

What should it take to describe a substance or product as ‘sperm safe’ Human Reproduction Update, Vol. 19, Supplement l pp. il-i48, 2013

Sperm Toxicity of ‘Nonspermicidal’ Lubricant and Ultrasound Gels Used in Reproductive Medicine. Fertility & Sterility. 2011;95:835-836

Quantitative Perceptual Differences Among Over-the-Counter Vaginal Products Using a Standardized Methodology. Contraception. 2011;84:184-193

Safety and Anti-HIV Activity of Over-the-Counter Lubricant Gels. International Microbicides Conference 2010 Abstract #347

Mucosal Irritation Potential of Personal Lubricants Relates to Product Osmolality as Detected by the Slug Mucosal Irritation Assay. Sexually Transmitted Diseases. 2008 May;35:512-516

Effect of Vaginal Lubricants on Sperm Motility and Chromatin Integrity: A Prospective Comparative Study. Fertility & Sterility. 2008 Feb;89:375-379

Prevalence of Vaginal Dryness in Trying-to-Conceive Couples. Pacific Coast Reproductive Society, April 2003